The number of individuals with dementia has more than doubled due to the rapidly increasing age of the population. This study aims to understand the secular trends in incidence and prevalence of dementia, Alzheimer’s disease, and vascular dementia in a Taiwanese population between 2002 and 2015. A population-based cross-sectional study was performed using the national health insurance research database between 2002 and 2015. Patients aged between 20 and 99 with dementia were identified. The multivariate Poisson regression was performed to explore the factors involved in predicting the incidence and prevalence of dementia and its subtypes. The age-standardized incidence of dementia, Alzheimer’s disease, and vascular dementia showed a rising trend from 2002 to 2015, revealing a 11.8%, 43.7%, and 12.7% increase, respectively. The age-adjusted prevalence of dementia and its subtypes also revealed an increasing pattern, showing a 91.2%, 127.9%, and 80.9% increase, respectively. The incidence of dementia and its subtypes increased with calendar year (adjusted incidence rate ratio [aIRR] = 1.01, 1.02, and 1.02, respectively, all P 0.001) and age (1.11, 112, and 1.11, respectively, all P 0.001). The male had the lower incident rate in dementia (aIRR=0.86) and Alzheimer’s disease (aIRR=0.76) but not vascular dementia (aIRR=1.07). It increased with age, particularly in those with hyperlipidemia, obesity, and alcoholism, with an approximately 3-fold aIRR. This study found that the incidence and prevalence of dementia increased with calendar year and age, as well as that females had a higher rate than males. The stronger age effect in incidents and prevalence of dementia was observed among those with hyperlipidemia, obesity, and alcoholism.

Authors:
Chyi-Huey Bai, Taipei Medical University, Taiwan
Yen-Chun Fan, Taipei Medical University, Taiwan

About the Presenter(s)
Chyi-Huey Bai is a Professor in the Department of Public Health at Taipei Medical University, Taiwan.

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