Background: Mobility is a key indicator of health in older adults, reflecting both physical capacity and interaction with the home environment. It is strongly associated with autonomy, functional status, and quality of life. However, conventional assessments rely on episodic clinical visits, which may fail to capture day-to-day variability and gradual functional decline, often delaying the detection of loss of independence. Continuous monitoring in real-life settings is therefore needed. Objective: To present preliminary results from the CART-France study and examine the relationship between in-home mobility measures and standard clinical assessments. Methods: CART-France aims to develop digital biomarkers for the longitudinal monitoring of intrinsic capacity in older adults. It is an ancillary study of the INSPIRE-T cohort and includes 120 community-dwelling participants aged 60 years and older. This preliminary analysis involved 15 participants with sufficient longitudinal data quality and follow-up continuity. In-home mobility was assessed using ambient sensors measuring (i) average walking speed via four aligned motion detectors and (ii) room-to-room transitions. Monthly aggregated data were used to derive instantaneous and cumulative mobility scores. Participants were classified according to their mobility trajectory using a rule-based approach. Digital biomarkers were compared with annual clinical assessments, including SPPB and gait speed. Results: Participants (80% women) had a mean age of 79.9 ± 4.8 years and a mean follow-up of 29.6 ± 6 months. Twelve showed stable mobility trajectories, whereas three showed a decline over time. Mobility scores were strongly correlated with clinical measures (Spearman’s ρ = 0.848).

Authors:
Abderrahim Derouiche, Chu-Toulouse, France
Eric Campo, LAAS-CNRS, France
Sophie Guyonnet, Chu-Toulouse, France
Isabelle Carrié, Chu-Toulouse, France
Antoine Piau, Clariane, France
Zara Steinmeyer, Chu-Toulouse, france

About the Presenter(s)
Abderrahim Derouiche is a Clinical Research Project Manager at CHU Toulouse. His interests include digital health, digital biomarkers, ambient sensing, and ageing. He is currently working on the CART-France project.

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